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  1. 21 Σεπ 2018 · Hypercalcemia of malignancy is most commonly mediated by tumoral production of parathyroid hormone–related protein or by cytokines activating osteoclast degradation of bone.

  2. 16 Απρ 2023 · The most common benign cause is PHPT, where patients are usually asymptomatic and have a long-standing history of mild hypercalcemia. Serum calcium levels greater than 13 mg/dL on initial presentation should raise suspicion of malignancy as the cause of hypercalcemia.

  3. Learn about hypercalcaemia, a serious but treatable condition caused by high blood calcium levels. Find out the symptoms, causes, treatments and cancers that are more likely to cause high calcium.

  4. Hypercalcemia of malignancy is a common finding typically found in patients with advanced stage cancers. We aimed to provide an updated review on the etiology, pathogenesis, clinical presentation, and management of malignancy-related hypercalcemia.

  5. 17 Νοε 2023 · Hypercalcemia affects up to 30% of patients with cancer. 1 It has been seen in most cancers but is most common in patients with non-small cell lung cancer, breast cancer, multiple myeloma, head...

  6. Elevated calcium levels can be an indicator of developing cancer. The main mechanism of hypercalcemia development in tumors appears to be excessive production of parathyroid hormone-related peptides.

  7. Hypercalcemia of malignancy (HCM) affects 2% to 30% of patients with cancer and is associated with high morbidity and mortality.

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