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21 Δεκ 2015 · The mass action equation is the building block from which all models of drug–receptor interaction are built. In the simplest case, the equation predicts a sigmoidal relationship between the amount of drug–receptor complex and the logarithm of the concentration of drug.
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The mass action equation as applied to the binding of a drug...
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A. Michaelis–Menten enzyme kinetics: k 1 = rate of...
- PMC Free Article
In addition, if given in sufficiently high concentration, an...
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22 Οκτ 2015 · The Law of Mass Action is relevant to various physiological and pharmacological concepts, including concentration–effect curves, dose–response curves, and ligand–receptor binding curves, all of which are important in describing the pharmacological actions of medications, the Langmuir adsorption isotherm, which describes the binding of ...
The mass action equation is the building block from which all models of drug receptor interaction are built. In the simplest case, the equation predicts a. sigmoidal relationship between the amount of drug receptor complex and the logarithm of the concentration of drug. The form of this function is also.
28 Ιουν 2015 · We have outlined four major categories of reasons that explain apparent non-dose-relatedness of adverse drug reactions, reconciling clinical observations with the law of mass action, which predicts dose responsiveness.
27 Οκτ 2015 · It is useful to demonstrate how the law of mass action is used to determine [AR] from the amount of drug ([A]) and receptor ([R]), where the receptor is the drug target (receptor, ion channel, enzyme).
1 Ιαν 2016 · We have traced the historical link between the Law of Mass Action and clinical pharmacology. The Law evolved from the work of the French chemist Claude Louis Berthollet, was first formulated by Cato Guldberg and Peter Waage in 1864 and later clarified by the Dutch chemist Jacobus van 't Hoff in 1877.
1 Ιαν 2016 · The relationships between drug potency in pharmacological models and the equilibrium dissociation constants defined in single mass action reactions are discussed. The mass action equation is the building block from which all models of drug–receptor interaction are built.
