Αποτελέσματα Αναζήτησης
15 Μαρ 2023 · Losartan is unusual in that grapefruit decreases its effects, potentially limiting its ability to control blood pressure . Eplerenone works similarly to losartan, but its levels increase when...
13 Ιουλ 2023 · Mixing grapefruit with some medicines can cause serious health problems. If you take prescription medicines, ask a health care professional, such as a doctor or pharmacist, whether it's OK to eat grapefruit or other citrus products while taking the medicines.
6 ημέρες πριν · Grapefruit juice can decrease blood levels of the active metabolite of losartan, potentially decreasing the clinical effects of losartan. Losartan is an inactive prodrug which must be metabolized to its active form, E-3174, to be effective.
15 Αυγ 2006 · Grapefruit can affect the metabolism of many medications, increasing the risk of toxicity and adverse effects. Learn how to manage grapefruit-drug interactions, especially for losartan and other calcium channel blockers, and find alternative drugs that do not interact with grapefruit.
Do not drink grapefruit juice if you're taking losartan. It may affect the levels of losartan in your blood and this may change how well it works and whether you have side effects. Apart from this and not drinking alcohol if you have side effects, there's nothing else you need to avoid while taking losartan.
There are many common drug interactions with grapefruit juice. Medicines that can interact include certain cholesterol medicines, antihistamines, migraine treatments or even cancer therapies. If you eat grapefruit or drink the juice, review your medications with a healthcare provider to rule out this common drug-food interaction.
Drugs that interact with grapefruit have all of the following characteristics: they are administered orally, they have very low to intermediate absolute bioavailability, and they are metabolized by the cytochrome P450 3A4 enzyme (CYP3A4).
