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30 Απρ 2024 · Naltrexone blocks the feelings of intoxication (the “buzz”) from alcohol when you drink it. This allows people with alcohol use disorder to lessen their drinking behaviors enough to stay in treatment, avoid relapses, and take their medication.
1 Δεκ 2022 · The article highlights the story of neuroscientist John Sinclair and his discovery that prescribing naltrexone 1 hour before drinking improves drinking outcomes by decreasing the reward of and cravings for alcohol, which may be especially helpful for binge drinkers.
3 Σεπ 2024 · Naltrexone — Naltrexone is an effective treatment in the management of alcohol use disorder . The preferable dosing schedule, its ability to be used in individuals who are still drinking, and its efficacy in individuals with co-occurring opioid use disorder make it an attractive agent for many.
13 Δεκ 2001 · Naltrexone was incorporated into the treatment of alcoholism on the premise that stimulation of the μ opioid receptor contributed to the rewarding effects of alcohol. 5–7 Data from clinical...
14 Αυγ 2008 · Naltrexone decreases craving and alcohol self-administration in alcohol-dependent subjects and activates the hypothalamo-pituitary-adrenocortical axis. Psychopharmacology (Berl)...
29 Μαρ 2024 · Naltrexone reduces alcohol cravings and the amount of alcohol consumed. Once a patient stops drinking, taking naltrexone helps patients maintain their sobriety. Naltrexone treatment lasts for three to four months. Practitioners should continue to monitor patients who are no longer taking naltrexone.
Naltrexone reduces both the rewarding effects of alcohol and craving for it. Brief History of Development. Naltrexone was first synthesized in 1963 by Endo Laboratories, which was acquired by DuPont in 1969.
