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12 Σεπ 2022 · Parvovirus B19 is a common virus that spreads from person to person. It’s mostly passed through respiratory secretions, like saliva, mucus, or sputum. These can spread when people cough or...
19 Απρ 2022 · Parvovirus infection is a common and highly contagious childhood illness. It's sometimes called slapped-cheek disease because of the distinctive face rash that develops. Parvovirus infection has also been known as fifth disease because, historically, it was fifth in a list of common childhood illnesses characterized by a rash.
Parvovirus B19 infection is usually mild for children and adults who are otherwise healthy. However, for some people, it can cause serious health complications affecting the nerves, joints, or blood system.
Parvovirus B19 spreads in the same way other respiratory viruses spread — through coughing, sneezing and touching things that someone with the virus touched. This includes surfaces, like countertops and doorknobs, and objects like toys or phones.
In humans the P antigen (also known as globoside) is the cellular receptor for parvovirus B19 virus that causes erythema infectiosum (fifth disease) in children. This infection is sometimes complicated by severe aplastic anemia caused by lysis of early erythroid precursors.
28 Ιουν 2023 · Vertical transmission of parvovirus B19 can occur from the mother to the fetus. Transmission is the highest before 20 weeks gestation. The virus blocks fetal erythropoiesis, leading to profound anemia, stillbirth, hydrops, and/or fetal death.
Human parvovirus B19 (B19V) is a human pathogen that belongs to genus Erythroparvovirus of the Parvoviridae family, which is composed of a group of small DNA viruses with a linear single-stranded DNA genome. B19V mainly infects human erythroid progenitor cells and causes mild to severe hematological disorders in patients.