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Laird was a faculty member at the University of Southern California (USC) from 1996 to 2014, where he served as professor of surgery, biochemistry and molecular biology; as Skirball-Kenis Professor of Cancer Research; as a program leader in epigenetics and regulation for the Norris Comprehensive Cancer Center; and as director of the USC ...
Laird was a faculty member at the University of Southern California (USC) from 1996 to 2014, where he served as professor of surgery, biochemistry and molecular biology; as Skirball-Kenis Professor of Cancer Research; as a program leader in epigenetics and regulation for the Norris Comprehensive Cancer Center; and as director of the USC ...
Peter LAIRD, Professor (Full) | Cited by 132,922 | of Van Andel Research Institute, Mi | Read 409 publications | Contact Peter LAIRD
Abstract. Methylation of cytosine bases in DNA provides a layer of epigenetic control in many eukaryotes that has important implications for normal biology and disease. Therefore, profiling DNA methylation across the genome is vital to understanding the influence of epigenetics.
To Κολόμπους (αγγλικά: Columbus, ορθή προφορά Κολάμπους) είναι πρωτεύουσα και μεγαλύτερη πόλη της αμερικανικής πολιτείας Οχάιο.
Peter W. Laird. USC Epigenome Center. USC/Norris Comprehensive Cancer Center Keck School of Medicine University of Southern California. DNA Methylation Alterations in Cancer. CpG Islands may acquire abnormal hypermethylation in cancer. Methylated CpG Island promoters are transcriptionally silenced in cancer.
The quantitative accuracy of real-time PCR and the ability to design bisulfite-dependent, DNA methylation-independent control reactions together allow for a quantitative assessment of these low frequency methylation events. Here we describe the experimental steps of MethyLight analysis in detail.
