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4 Οκτ 2024 · Minipress (prazosin), a drug commonly used to treat high blood pressure and urinary retention, has been shown in some studies to be safe and effective in managing nightmares and sleep disturbances in people with post-traumatic stress disorder (PTSD).
Articles met criteria for inclusion if prazosin was used to treat nightmares, and outcome measures included nightmares or related symptoms of sleep disorders. Our search yielded 21 studies, consisting of 4 RCTs, 4 open-label studies, 4 retrospective chart reviews, and 9 single case reports.
Prazosin has been recommended for treatment of PTSD-associated nightmares (Level A) , but the recent highly recognized PACT trial reported that prazosin did not alleviate distressing dreams nor improve sleep quality in military veterans with chronic PTSD .
17 Μαρ 2023 · Used to treat hypertension, this alpha-blocker may offer other added benefits – including relief from certain sleep disturbances. In this article, we’ll look closer at Prazosin for sleep to determine if this medication is a safe option for easing insomnia symptoms and helping you improve your sleep quality.
Prazosin for treating sleep disturbances in adults with posttraumatic stress disorder: a systematic review and meta-analysis of randomized controlled trials. Davit Khachatryan 1 , Dianne Groll 2 , Linda Booij 3 , Amir A Sepehry 4 , Christian G Schütz 5. Affiliations Expand.
1 Ιουλ 2024 · Prazosin may be the most effective treatment for insomnia (SMD = −0.88, 95%CI = [-1.22;-0.54], nightmares (SMD = −0.44, 95%CI = [-0.84;-0.04]) and poor sleep quality (SMD = −0.55, 95%CI = [-1.01;-0.10]).
Prazosin was well-tolerated and associated with improvements in nightmares and sleep in youth with PTSD. Adverse events were consistent with the known side-effect profile of prazosin and included dizziness and nausea. Keywords: Nightmares, Posttraumatic stress disorder, Prazosin, Sexual abuse, Sleep disturbances, Trauma. Introduction
