Διαφήμιση
σχετικά με: pten genePurified plasmids ready for transfection, no need for bacterial handling. Multiple tag and promoter Options, Lenti particles available.
Αποτελέσματα Αναζήτησης
Phosphatase and tensin homolog (PTEN) is a phosphatase in humans and is encoded by the PTEN gene. [6] Mutations of this gene are a step in the development of many cancers , specifically glioblastoma, lung cancer, breast cancer, and prostate cancer.
2 Οκτ 2024 · PTEN is a tumor suppressor gene that encodes a phosphatase that dephosphorylates phosphoinositides and proteins. It is involved in various pathways and diseases, and has multiple transcript variants and aliases.
The PTEN gene provides instructions for making an enzyme that helps regulate cell division and prevent tumor formation. Mutations in the gene can cause various conditions, such as Bannayan-Riley-Ruvalcaba syndrome, Cowden syndrome, autism spectrum disorder, and prostate cancer.
Phosphatase and tensin homolog deleted on chromosome ten (PTEN) is a phosphatase that is frequently altered in cancer. PTEN has phosphatase-dependent and - independent roles; and genetic alterations in PTEN lead to deregulation of protein synthesis, ...
1 Ιουν 2018 · PTEN is one of the most frequently mutated tumour suppressor genes in human cancer. It was identified simultaneously by three groups in 1997 as a candidate tumour suppressor gene 1, 2...
Phosphatase and Tensin Homolog deleted on Chromosome 10 (PTEN) is a dual phosphatase with both protein and lipid phosphatase activities. PTEN reduces the level of PI-3, 4, 5-P 3, a critical 2nd messenger mediating the signal of not only growth factors but also that of insulin.
PTEN stands for Phosphatase and TENsin homolog deleted on chromosome 10 and is a classical tumor suppressor gene located in the 10q23 region of chromosome 10 encoding for a 403-aminoacid multifunctional protein (predicted MW 47 kDa), which possesses lipid and protein phosphatase activities.
Διαφήμιση
σχετικά με: pten genePurified plasmids ready for transfection, no need for bacterial handling. Multiple tag and promoter Options, Lenti particles available.
