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8 Απρ 2019 · Pyruvate is a three-carbon molecule with a carboxylic acid and a ketone group. It is produced by glycolysis and amino acid metabolism, and can enter the citric acid cycle, fermentation or gluconeogenesis.
Pyruvate is a 2-oxo monocarboxylic acid anion that is the conjugate base of pyruvic acid, which is an important metabolic product for energy-producing biochemical pathways. Pyruvate is the final product of glycolysis and, when hypoxic conditions arise, can be metabolized anaerobically to form lactate .
Pyruvic acid (CH 3 COCOOH) is the simplest of the alpha-keto acids, with a carboxylic acid and a ketone functional group. Pyruvate, the conjugate base, CH 3 COCOO −, is an intermediate in several metabolic pathways throughout the cell.
1 Ιουν 2023 · Pyruvate Structure. Pyruvate has a very simple chemical structure and it is the conjugate base of pyruvic acid. Three carbon molecules are composed of a ketone functional group and a carboxyl group present in the structure of pyruvate.
Pyruvic acid or pyruvate is a key intermediate in the glycolytic and pyruvate dehydrogenase pathways, which are involved in biological energy production. Pyruvate is widely found in living organisms. It is not an essential nutrient since it can be synthesized in the cells of the body.
How pyruvate from glycolysis is converted to acetyl CoA so it can enter the citric acid cycle. Pyruvate is modified by removal of a carboxyl group followed by oxidation, and then attached to Coenzyme A.
Molecular Structure and Function of Pyruvate in Cellular Respiration. Pyruvate has a simple molecular structure, consisting of a three-carbon compound with a carboxyl group at one end. The carboxyl group contains a carbon atom double-bonded to an oxygen atom and single-bonded to a hydroxyl group.