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How pyruvate from glycolysis is converted to acetyl CoA so it can enter the citric acid cycle. Pyruvate is modified by removal of a carboxyl group followed by oxidation, and then attached to Coenzyme A.
28 Φεβ 2021 · Learn how pyruvate, the product of glycolysis, is converted into acetyl CoA in mitochondria and enters the citric acid cycle for further catabolism. See the three-step process, the products, and the contributors of pyruvate oxidation.
18 Δεκ 2021 · Learn how pyruvate, the product of glycolysis, is converted into acetyl CoA and enters the citric acid cycle in mitochondria. The cycle is a closed loop that oxidizes acetyl CoA and produces carbon dioxide, NADH, FADH2, and ATP.
Key Points. In the conversion of pyruvate to acetyl CoA, each pyruvate molecule loses one carbon atom with the release of carbon dioxide. During the breakdown of pyruvate, electrons are transferred to NAD+ to produce NADH, which will be used by the cell to produce ATP.
Learn how pyruvate, the product of glycolysis, is converted into acetyl CoA in the presence of oxygen. Acetyl CoA enters the citric acid cycle for further catabolism and ATP production.
Pyruvate decarboxylation or pyruvate oxidation, also known as the link reaction (or oxidative decarboxylation of pyruvate [1]), is the conversion of pyruvate into acetyl-CoA by the enzyme complex pyruvate dehydrogenase complex. [2] [3] The reaction may be simplified as: Pyruvate + NAD + + CoA → Acetyl-CoA + NADH + CO 2