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  1. 11 Νοε 2019 · “Small heart syndrome” is defined as a small heart shadow on chest X-ray with a cardiothoracic ratio of ≤42%, which indicates orthostatic intolerance (1). In such cases, the renin-aldosterone system is markedly downregulated despite a reduced cardiac output (2).

  2. 28 Νοε 2011 · High prevalence of lower cardiac index <2 in the CFS patients with OI (65%) suggests that these patients have a more severe form of small heart, with impaired systemic circulation and cerebral hypoperfusion while in an upright position, than the patients with simple OI.

  3. Small heart syndrome may contribute to the development of CFS as a constitutional factor predisposing to fatigue, and may be included in the genesis of CFS. A considerable number of CFS patients have a small heart.

  4. 7 Ιαν 2011 · Low cardiac output due to a small LV can be a cause of the symptoms exhibited by patients with small heart syndrome. Various triggers including loss of appetite, diarrhea and summer sweating can cause dehydration resulting in preload reduction.

  5. 7 Ιαν 2011 · Cardiac Output, Low / diagnosis* Diagnosis, Differential Fatigue Syndrome, Chronic / complications

  6. 7 Ιαν 2011 · The prevalence of low cardiac index (< 2) was significantly (p < 0.01) higher in S (60%) than in M (9%) and C (4%). The pathognomonic significance of a small heart should be recognized as a constitutional factor that predisposes individuals to low output syndrome.

  7. 1 Σεπ 2021 · Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a medically unexplained illness characterized by severe fatigue limiting normal daily activities among other symptoms.

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