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  1. Sodium bicarbonate is a systemic alkalizer, which increases plasma bicarbonate, buffers excess hydrogen ion concentration, and raises blood pH, thereby reversing the clinical manifestations of acidosis.

  2. 12 Φεβ 2024 · Due to its ability to buffer pH and influence acid-base shifts, sodium bicarbonate can also affect many drug-drug interactions, including fluoroquinolones such as levofloxacin and tetracyclines such as doxycycline and minocycline.

  3. 17 Μαρ 2024 · Sodium bicarbonate is essential in treating various conditions, including metabolic acidosis, hyperkalemia, drug toxicity, and certain off-label uses like tricyclic antidepressant overdose.

  4. 12 Φεβ 2024 · Study Guide. Sodium bicarbonate is a multifaceted medication that plays a crucial role in managing and treating diverse disease pathologies. This activity delves into the expansive applications of sodium bicarbonate, providing healthcare professionals with a nuanced understanding of its indications, mechanism of ….

  5. 9 Απρ 2020 · We tested whether oral sodium bicarbonate provides net health benefit for older people with advanced chronic kidney disease and serum bicarbonate concentrations < 22 mmol/L. Pragmatic multicentre, parallel group, double-blind, placebo-controlled randomised trial.

  6. BiCARB is a multi-centre, double-blind, placebo controlled, randomised trial evaluating the clinical and cost-effectiveness of oral sodium bicarbonate in the management of older people with chronic kidney disease and severely reduced glomerular filtration rate (GFR) who have a mild degree of metabolic acidosis.

  7. 9 Απρ 2020 · We tested whether oral sodium bicarbonate provides net health benefit for older people with advanced chronic kidney disease and serum bicarbonate concentrations < 22 mmol/L. Methods: Pragmatic multicentre, parallel group, double-blind, placebo-controlled randomised trial.

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