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Hemolytic uremic syndrome (HUS) is a rare and severe form of thrombotic microangiopathy associated with a poor renal prognosis. It is characterized by the association of mechanical hemolytic anemia, thrombocytopenia, and kidney failure (1).
- Hemolytic Uremic syndrome associated with pregnancy: Outcome from acute ...
To report here, case series of women developing acute kidney...
- Pregnancy in uremic patients: an eventful journey - PubMed
Renal damage, which can be caused by gestational anomalies...
- Hemolytic Uremic syndrome associated with pregnancy: Outcome from acute ...
Atypical hemolytic uremic syndrome (aHUS), a challenging disorder, commonly caused by inherited defects or regulatory processes of the complement alternative pathway. There are multiple causes, including pregnancy.
Pregnancy-associated atypical hemolytic uremic syndrome usually presents in the postpartum period, often after a pregnancy complication, and eculizumab is effective for achieving disease remission.
To report here, case series of women developing acute kidney injury (AKI) in association with hemolytic uremic syndrome (HUS) during pregnancy or within days postpartum.
Women with renal disorders face several challenges in pregnancy due to increased physiologic demands on the kidney and risk for disease progression, the potential teratogenicity of medications, and the increased risk of complications such as preeclampsia and preterm delivery.
Renal damage, which can be caused by gestational anomalies such as pre-eclampsia, carries a risk of gestational complications; the greatest risk being in women who become pregnant while on hemodialysis or peritoneal dialysis.
10 Ιαν 2018 · We present a teaching case of atypical hemolytic uremic syndrome in the postpartum period in a young woman who was found to have mutations of uncertain clinical significance in the complement cascade, including in C3, CFH, and CFI.
