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Inhibin, hormone secreted by the granulosa cells in the ovaries of women that acts primarily to inhibit the secretion of follicle-stimulating hormone by the anterior pituitary gland. Since the major action of follicle-stimulating hormone is to stimulate the formation and function of granulosa.
- Follicle-Stimulating Hormone
follicle-stimulating hormone (FSH), one of two gonadotropic...
- Follicle-Stimulating Hormone
Activin is produced in the gonads, pituitary gland, placenta, and other organs: In the ovarian follicle, activin increases FSH binding and FSH-induced aromatization. It participates in androgen synthesis enhancing LH action in the ovary and testis. In the male, activin enhances spermatogenesis.
1 Μαρ 2005 · Inhibins are gonadal hormones that regulate FSH secretion and have paracrine effects in the ovary, testis and placenta. They are involved in gametogenesis, conception, implantation and early pregnancy, and their levels can be used as markers for fertility and pregnancy outcomes.
Inhibins are glycoprotein hormones of which there are two molecular forms, inhibin A and inhibin B. Classically, inhibin is known to have a negative feedback effect on pituitary follicle-stimulating hormone secretion. The fetoplacental unit produces inhibin throughout pregnancy.
Inhibin is a 32-kD dimeric (α and β subunits) glycoprotein produced by ovarian granulosa cells, testicular Sertoli cells, and, to a lesser degree, testicular Leydig cells. It inhibits the release of follicle-stimulating hormone from the pituitary-inhibiting folliculogenesis.
Inhibin is a dimeric glycoprotein that suppresses follicle-stimulating hormone (FSH) secretion from the pituitary. Two bioactive forms of inhibin exist, inhibin A and B. The availability of specific immunoassays for each of the isoforms has enabled the study of the individual inhibins and their physiological roles.
Inhibin is best known as a reproductive hormone that inhibits release of follicle-stimulating hormone (FSH) from the pituitary gland. Over the last decade or so a number of other biological roles have emerged, putting inhibin more in the class of a growth factor.
