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  1. Ex vivo gene therapy refers to the process of removing specific cells from a person, genetically altering them in a laboratory, and then transplanting them back into the person. 2,3 Ex vivo gene therapy works by genetically modifying a patient’s stem cells, which then replace target cells that have a missing or malfunctioning gene 2,3

  2. 23 Μαρ 2023 · Broadly, gene therapies are techniques used to treat or prevent disease by tweaking the content or expression of cells' DNA, often by replacing faulty genes with...

  3. This review will summarize the advent and clinical translation of ex vivo gene therapy, with the focus on the milestones during the exploitation of genetically engineered hematopoietic stem cells (HSCs) tackling a variety of pathological conditions which led to marketing approval.

  4. 26 Οκτ 2021 · Ex vivo gene therapy involves removing blood, bone marrow or other tissues from a patient, isolating the cells of interest and correcting them in the lab before reinfusing them back into...

  5. 20 Αυγ 2013 · The progression in the field of gene therapy have developed into two different strategies: ex vivo and in vivo gene therapy. 20 Ex vivo gene therapy includes the harvesting of cells from a patient followed subsequently by genetically modification ex vivo in a laboratory.

  6. 16 Νοε 2020 · For ex vivo approaches (left panel), autologous cells can be isolated directly from the patient and genetically modified to elicit a therapeutic effect, while allogeneic cells can be produced...

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